Everything about Aspergillus Fumigatus totally explained
Aspergillus fumigatus is a
fungus of the
genus Aspergillus, and is one of the most common
Aspergillus species to cause disease in
immunocompromised individuals.
A. fumigatus has a stable
haploid genome, with no known sexual cycle, and reproduces by forming
conidiospores that are released into the environment. Capable of growth at 37°C (human body temperature), spores are common inhalation pollutants; typically, however, these are quickly eliminated by the immune system in healthy individuals.
When the fermentation broth of
A. fumigatus was screened, a number of
indolic alkaloids with anti-
mitotic properties were discovered. The compounds of interest have been of a class known as tryprostatins, with
spirotryprostatin B being of special interest as an anti-cancer drug.
Genome
The genome sequences of three
Aspergillus species—
Aspergillus fumigatus,
Aspergillus nidulans, and
Aspergillus oryzae—were published in the journal
Nature in December 2005.
Gallery
Image:Aspergillus fumigatus 01.jpg
Image:Conidia phialoconidia of Aspergillus fumigatus PHIL 300 lores.jpg|Conidia phialoconidia of Aspergillus fumigatus
Image:070522-aspergillus 009.jpg|Colony in Petri dish
Image:Aspergillus fumigatus.jpg|Aspergillus fumigatus isolated from woodland soil
Further Information
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